Synthesis of the Side Chain of a Novel Carbapenem via Iodine-Mediated Oxidative Cyclization of (1R)-N-(1-Aryl-3-butenyl)acetamide.
Author:
Affiliation:
1. Banyu Tsukuba Research Institute
Publisher
Pharmaceutical Society of Japan
Subject
Drug Discovery,General Chemistry,General Medicine
Link
http://www.jstage.jst.go.jp/article/cpb/50/3/50_3_423/_pdf
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1. Discovery of novel trans -3,5-disubstituted pyrrolidinylthio-1β-methylcarbapenems
2. Synthesis of J-111,347, a Novel 1.BETA.-Methylcarbapenem with Broad-spectrum Antibacterial Activity.
3. Stereoselective Synthesis of a Broad Spectrum 1β-Methylcarbapenem, J-114,870
4. Allylsilanes derived from aminoacids in the synthesis of piperidine and pyrrolidins derivatives
5. Concise stereoselective synthesis of (2S,4R)-4-hydroxyproline from (S)-O-benzylglycidol a novel cyclization
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