Protection of Baculovirus Vectors Expressing Complement Regulatory Proteins against Serum Complement Attack
Author:
Affiliation:
1. School of Pharmacy, Kanazawa University
2. Electron Microscope Room, Institute of Tropical Medicine, Nagasaki University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/41/10/41_b18-00451/_pdf
Reference18 articles.
1. 1) Chen CY, Lin CY, Chen GY, Hu YC. Baculovirus as a gene delivery vector: recent understandings of molecular alterations in transduced cells and latest applications. Biotechnol. Adv., 29, 618–631 (2011).
2. 2) Ricklin D, Hajishengallis G, Yang K, Lambris JD. Complement: a key system for immune surveillance and homeostasis. Nat. Immunol., 11, 785–797 (2010).
3. 3) Hofmann C, Strauss M. Baculovirus-mediated gene transfer in the presence of human serum or blood facilitated by inhibition of the complement system. Gene Ther., 5, 531–536 (1998).
4. 4) Hoare J, Waddington S, Thomas HC, Coutelle C, McGarvey MJ. Complement inhibition rescued mice allowing observation of transgene expression following intraportal delivery of baculovirus in mice. J. Gene Med., 7, 325–333 (2005).
5. 5) Stoermer KA, Morrison TE. Complement and viral pathogenesis. Virology, 411, 362–373 (2011).
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