Direct Activation of the Large-Conductance Calcium-Activated Potassium Channel by Flavonoids Isolated from Sophora flavescens
Author:
Affiliation:
1. School of Life Sciences and National Leading Research Laboratory, Gwangju Institute of Science and Technology (GIST)
2. Department of Food Science and Nutrition, Pukyong National University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/41/8/41_b18-00250/_pdf
Reference18 articles.
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3. 3) Meredith AL, Thorneloe KS, Werner ME, Nelson MT, Aldrich RW. Overactive bladder and incontinence in the absence of the BK large conductance Ca2+-activated K+ channel. J. Biol. Chem., 279, 36746–36752 (2004).
4. 4) dela Peña IC, Yoon SY, Kim SM, Lee GS, Ryu JH, Park CS, Kim YC, Cheong JH. Bladder-relaxant properties of the novel benzofuroindole analogue LDD175. Pharmacology, 83, 367–378 (2009).
5. 5) Lee S, Chae MR, Lee BC, Kim YC, Choi JS, Lee SW, Cheong JH, Park CS. Urinary bladder-relaxant effect of kurarinone depending on potentiation of large-conductance Ca2+-activated K+ channels. Mol. Pharmacol., 90, 140–150 (2016).
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