High Throughput Screening of Pharmacokinetics and Metabolism in Drug Discovery (I) —Establishment of Assessment System for Absorption to Compounds with a Wide Diversity of Physical Properties

High Throughput Screening of Pharmacokinetics and Metabolism in Drug Discovery (I) —Establishment of Assessment System for Absorption to Compounds with a Wide Diversity of Physical Properties—

Published:2005-01-01 Issue:1 Volume:125 Page:121-130
ISSN:0031-6903
Container-title:YAKUGAKU ZASSHI
language:en
Short-container-title:YAKUGAKU ZASSHI

Author:

KOMURA Hiroshi¹,KAWAHARA Iichiro¹,SHIGEMOTO Yukie¹,MATSUDA Kenichi¹,ANO Rieko¹,MURAYAMA Yoko¹,MORIWAKI Toshiya¹,YOSHIDA Nagahiro H.¹

Affiliation:

1. Department of Research Pharmacokinetics, Research Center Kyoto, Bayer Yakuhin, Ltd.

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology

Link

https://www.jstage.jst.go.jp/article/yakushi/125/1/125_1_121/_pdf

Reference27 articles.

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2. 2) Lipinski C. A., J. Pharmacol. Toxicol. Methods, 44, 235-249 (2000).

3. 3) Kerns E. H., Di L., Drug Discov. Today, 8, 316-323 (2003).

4. 4) Kariv I., Rourck R. A., Kassel D. B., Chung T. D., Combi. Chem. High Throughput Screen, 5, 459-472 (2002).

5. 5) Panchagnula R., Thomas N. S., Int. J. Pharm., 201, 131-150 (2000).

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