Inefficiency in GM2 Ganglioside Elimination by Human Lysosomal .BETA.-Hexosaminidase .BETA.-Subunit Gene Transfer to Fibroblastic Cell Line Derived from Sandhoff Disease Model Mice-Reference-Cited by-同舟云学术

Inefficiency in GM2 Ganglioside Elimination by Human Lysosomal .BETA.-Hexosaminidase .BETA.-Subunit Gene Transfer to Fibroblastic Cell Line Derived from Sandhoff Disease Model Mice

Published:2006 Issue:8 Volume:29 Page:1564-1569
ISSN:0918-6158
Container-title:Biological and Pharmaceutical Bulletin
language:en
Short-container-title:Biol. Pharm. Bull.

Author:

Itakura Tomohiro¹,Kuroki Aya¹,Ishibashi Yasuhiro¹²,Tsuji Daisuke¹²,Kawashita Eri¹,Higashine Yukari¹,Sakuraba Hitoshi³²,Yamanaka Shoji⁴,Itoh Kohji¹²

Affiliation:

1. Department of Medicinal Biotechnology, Institute for Medicinal Resources, Graduate School of Pharmaceutical Sciences, The University of Tokushima

2. CREST, JST

3. Department of Clinical Genetics, The Tokyo Metropolitan Institute of Medical Science, Tokyo Metropolitan Organization for Medical Research

4. Division of Anatomic and Surgical Pathology, Hospital of Yokohama City University School of Medicine

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

http://www.jstage.jst.go.jp/article/bpb/29/8/29_8_1564/_pdf

Reference44 articles.

1. Biochemical consequences of mutations causing the GM2 gangliosidoses

2. Evidence for two different active sites on human beta-hexosaminidase A. Interaction of GM2 activator protein with beta-hexosaminidase A.

3. Structural Organization, Sequence, and Expression of the Mouse HEXA Gene Encoding the α Subunit of Hexosaminidase A

4. Structure and Expression of the Mouse β-Hexosaminidase Genes, Hexa and Hexb

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