Synthesis of (-)-Epibatidine and Its Derivatives from Chiral Allene-1,3-dicarboxylate Esters
Author:
Affiliation:
1. Department of Pharmaceutical Manufacturing Chemistry, 21st Century COE Program, Kyoto Pharmaceutical University
Publisher
Pharmaceutical Society of Japan
Subject
Drug Discovery,General Chemistry,General Medicine
Link
http://www.jstage.jst.go.jp/article/cpb/54/3/54_3_399/_pdf
Reference32 articles.
1. Epibatidine: a novel (chloropyridyl)azabicycloheptane with potent analgesic activity from an Ecuadoran poison frog
2. Synthesis of a Novel N-Hydroxypyrrole via Lithium Perchlorate Accelerated Diels-Alder Methodology
3. Ernest Guenther Award in Chemistry of Natural Products. Amphibian Skin: A Remarkable Source of Biologically Active Arthropod Alkaloids
4. Stereocontrolled total synthesis of (+)- and (-)-epibatidine
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