Effects of β-Naphthoflavone on Ugt1a6 and Ugt1a7 Expression in Rat Brain
Author:
Affiliation:
1. Department of Pharmaceutics, Faculty of Pharmacy, Meijo University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/39/1/39_b15-00578/_pdf
Reference40 articles.
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2. 2) King CD, Rios GR, Assouline JA, Tephly TR. Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate. Arch. Biochem. Biophys., 365, 156–162 (1999).
3. 3) Suleman FG, Abid A, Gradinaru D, Daval JL, Magdalou J, Minn A. Identification of the uridine diphosphate glucuronosyltransferase isoform UGT1A6 in rat brain and in primary cultures of neurons and astrocytes. Arch. Biochem. Biophys., 358, 63–67 (1998).
4. 4) Uchihashi S, Nishikawa M, Sakaki T, Ikushiro S. Comparison of serotonin glucuronidation activity of UDP-glucuronosyltransferase 1a6a (Ugt1a6a) and Ugt1a6b: evidence for the preferential expression of Ugt1a6a in the mouse brain. Drug Metab. Pharmacokinet., 28, 260–264 (2013).
5. 5) Court MH, Duan SX, von Moltke LL, Greenblatt DJ, Patten CJ, Miners JO, Mackenzie PI. Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms. J. Pharmacol. Exp. Ther., 299, 998–1006 (2001).
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