Denatonium and 6-<i>n</i>-Propyl-2-thiouracil, Agonists of Bitter Taste Receptor, Inhibit Contraction of Various Types of Smooth Muscles in the Rat and Mouse-Reference-Cited by-同舟云学术

Denatonium and 6-n-Propyl-2-thiouracil, Agonists of Bitter Taste Receptor, Inhibit Contraction of Various Types of Smooth Muscles in the Rat and Mouse

Published:2016 Issue:1 Volume:39 Page:33-41
ISSN:0918-6158
Container-title:Biological & Pharmaceutical Bulletin
language:en
Short-container-title:Biol. Pharm. Bull.

Author:

Sakai Hiroyasu¹,Sato Ken¹,Kai Yuki¹,Chiba Yoshihiko²,Narita Minoru³

Affiliation:

1. Department of Analytical Pathophysiology, Division of Pharmacy Professional Development and Research, Hoshi University

2. Department of Biology, Hoshi University

3. Department of Pharmacology, Hoshi University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

https://www.jstage.jst.go.jp/article/bpb/39/1/39_b15-00426/_pdf

Reference22 articles.

1. 1) Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, Bufe B, Appendino G, Behrens M. The molecular receptive ranges of human TAS2R bitter taste receptors. Chem. Senses, 35, 157–170 (2010).

2. 2) Wong GT, Gannon KS, Margolskee RF. Transduction of bitter and sweet taste by gustducin. Nature, 381, 796–800 (1996).

3. 3) Chandrashekar J, Mueller KL, Hoon MA, Adler E, Feng L, Guo W, Zuker CS, Ryba NJ. T2Rs function as bitter taste receptors. Cell, 100, 703–711 (2000).

4. 4) Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. Cell, 112, 293–301 (2003).

5. 5) Deshpande DA, Wang WC, McIlmoyle EL, Robinett KS, Schillinger RM, An SS, Sham JS, Liggett SB. Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction. Nat. Med., 16, 1299–1304 (2010).

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