<i>S</i>-Allyl-L-cysteine Promotes Cell Proliferation by Stimulating Growth Hormone Receptor/Janus Kinase 2/Phospholipase C Pathways and Promoting Insulin-Like Growth Factor Type-I Secretion in Primary Cultures of Adult Rat Hepatocytes
Author:
Affiliation:
1. Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Josai University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/45/5/45_b21-01071/_pdf
Reference48 articles.
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2. 2) Ullrich A, Gray A, Tam AW, Yang-Feng T, Tsubokawa M, Collins C, Henzel W, Le Bon T, Kathuria S, Chen E. Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J., 5, 2503–2512 (1986).
3. 3) Neubauer J. Exercise effects on muscle insulin signaling and action Invited Review: autocrine/paracrine IGF-I and skeletal muscle adaptation. J. Appl. Physiol., 90, 1593–1599 (2001).
4. 4) Herrington J, Carter-Su C. Signaling pathways activated by the growth hormone receptor. Trends Endocrinol. Metab., 12, 252–257 (2001).
5. 5) Fausto N, Campbell JS, Riehle KJ. Liver regeneration. Hepatology, 43 (Suppl. 1), S45–S53 (2006).
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1. Cell proliferation effects of S-allyl-L-cysteine are associated with phosphorylation of janus kinase 2, insulin-like growth factor type-I receptor tyrosine kinase, and extracellular signal-regulated kinase 2 in primary cultures of adult rat hepatocytes;European Journal of Pharmacology;2022-07
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