Functional Interaction between Cytochrome P450 and UDP-Glucuronosyltransferase on the Endoplasmic Reticulum Membrane: One of Post-translational Factors Which Possibly Contributes to Their Inter-Individual Differences-Reference-Cited by-同舟云学术

Functional Interaction between Cytochrome P450 and UDP-Glucuronosyltransferase on the Endoplasmic Reticulum Membrane: One of Post-translational Factors Which Possibly Contributes to Their Inter-Individual Differences

Published:2021-11-01 Issue:11 Volume:44 Page:1635-1644
ISSN:0918-6158
Container-title:Biological and Pharmaceutical Bulletin
language:en
Short-container-title:Biol. Pharm. Bull.

Author:

Miyauchi Yuu¹,Takechi Shinji¹,Ishii Yuji²

Affiliation:

1. Laboratory of Hygienic Chemistry, Faculty of Pharmaceutical Sciences, Sojo University

2. Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

https://www.jstage.jst.go.jp/article/bpb/44/11/44_b21-00286/_pdf

Reference98 articles.

1. 1) Williams JA, Hyland R, Jones BC, Smith DA, Hurst S, Goosen TC, Peterkin V, Koup JR, Ball SE. Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios. Drug Metab. Dispos., 32, 1201–1208 (2004).

2. 2) Foti RS, Dalvie DK. Cytochrome P450 and non-cytochrome P450 oxidative metabolism: contributions to the pharmacokinetics, safety, and efficacy of xenobiotics. Drug Metab. Dispos., 44, 1229–1245 (2016).

3. 3) Evans WE, Relling MV. Pharmacogenomics: translating functional genomics into rational therapeutics. Science, 286, 487–491 (1999).

4. 4) Court MH. Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system. Drug Metab. Rev., 42, 209–224 (2010).

5. 5) Sakamoto A, Matsumaru T, Ishiguro N, Schaefer O, Ohtsuki S, Inoue T, Kawakami H, Terasaki T. Reliability and robustness of simultaneous absolute quantification of drug transporters, cytochrome P450 enzymes, and Udp-glucuronosyltransferases in human liver tissue by multiplexed MRM/selected reaction monitoring mode tandem mass spectrometry with nano-liquid chromatography. J. Pharm. Sci., 100, 4037–4043 (2011).

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Metabolism of highly potent synthetic opioid nitazene analogs: N‐ethyl‐N‐(1‐glucuronyloxyethyl) metabolite formation and degradation to N‐desethyl metabolites during enzymatic hydrolysis;Drug Testing and Analysis;2024-04-28

2. The drug disposition in the Spleen: A novel study of CYP and UGT-mediated drug metabolism;2024-04-20

3. Emerging role of the crosstalk between gut microbiota and liver metabolome of subterranean herbivores in response to toxic plants;Ecotoxicology and Environmental Safety;2024-01

4. UDP-Glycosyltransferases;Reference Module in Biomedical Sciences;2024

5. Functional characterization of CYP1 enzymes: Complex formation, membrane localization and function;Journal of Inorganic Biochemistry;2023-10