PI3K/AKT1 Signaling Pathway Mediates Sinomenine-Induced Hepatocellular Carcinoma Cells Apoptosis: An in Vitro and in Vivo Study-Reference-Cited by-同舟云学术

PI3K/AKT1 Signaling Pathway Mediates Sinomenine-Induced Hepatocellular Carcinoma Cells Apoptosis: An in Vitro and in Vivo Study

Published:2022-05-01 Issue:5 Volume:45 Page:614-624
ISSN:0918-6158
Container-title:Biological and Pharmaceutical Bulletin
language:en
Short-container-title:Biological & Pharmaceutical Bulletin

Author:

Luo Yan¹,Liu Liwei²,Zhao Jihua³,Jiao Yue⁴,Zhang Meiyu⁴,Xu Guangli³,Jiang Yumao¹

Affiliation:

1. Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences

2. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences

3. The First Affiliated Hospital of Henan University of Chinese Medicine

4. Beijing Key Laboratory of Traditional Chinese Medicine Basic Research on Prevention and Treatment of Major Diseases, Experimental Research Center, China Academy of Chinese Medical Sciences

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

https://www.jstage.jst.go.jp/article/bpb/45/5/45_b21-01063/_pdf

Reference39 articles.

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2. 2) Sartorius K, Sartorius B, Aldous C, Govender PS, Madiba TE. Global and country underestimation of hepatocellular carcinoma (HCC) in 2012 and its implications. Cancer Epidemiol., 39, 284–290 (2015).

3. 3) de Lope CR, Tremosini S, Forner A, Reig M, Bruix J. Management of HCC. J. Hepatol., 56 (Suppl. 1), S75–S87 (2012).

4. 4) Yamasaki H. Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum. Acta Med. Okayama, 30, 1–20 (1976).

5. 5) Xu M, Liu L, Qi C, Deng B, Cai X. Sinomenine versus NSAIDs for the treatment of rheumatoid arthritis: a systematic review and meta-analysis. Planta Med., 74, 1423–1429 (2008).

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