Amyloid Beta-Peptide 25–35 (Aβ25–35) Induces Cytotoxicity via Multiple Mechanisms: Roles of the Inhibition of Glucosylceramide Synthase by Aβ25–35 and Its Protection by D609-Reference-Cited by-同舟云学术

Amyloid Beta-Peptide 25–35 (Aβ_25–35) Induces Cytotoxicity via Multiple Mechanisms: Roles of the Inhibition of Glucosylceramide Synthase by Aβ_25–35 and Its Protection by D609

Published:2021-10-01 Issue:10 Volume:44 Page:1419-1426
ISSN:0918-6158
Container-title:Biological and Pharmaceutical Bulletin
language:en
Short-container-title:Biol. Pharm. Bull.

Author:

Tang Zhihui¹,Motoyoshi Kaisei¹,Honda Takuya¹,Nakamura Hiroyuki¹,Murayama Toshihiko¹

Affiliation:

1. Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

https://www.jstage.jst.go.jp/article/bpb/44/10/44_b21-00204/_pdf

Reference41 articles.

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3. 3) Smith AK, Khayat E, Lockhart C, Klimov DK. Do cholesterol and sphingomyelin change the mechanism of Aβ_25–35 peptide binding to zwitterionic bilayer? J. Chem. Inf. Model., 59, 5207–5217 (2019).

4. 4) Hannun YA, Obeid LM. Principles of bioactive lipid signaling: lessons from sphingolipids. Nat. Rev. Mol. Cell Biol., 9, 139–150 (2008).

5. 5) Hannun YA, Obeid LM. Sphingolipids and their metabolism in physiology and disease. Nat. Rev. Mol. Cell Biol., 19, 175–191 (2018).

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