Impact of Gut Microbiota on the Pharmacokinetics of Glycyrrhizic Acid in Yokukansan, a Kampo Medicine
Author:
Affiliation:
1. Department of Pharmacy, Kochi Medical School Hospital
2. Graduate school of Integrated Arts and Sciences, Kochi University
3. Tsumura Advanced Technology Research Laboratories, Tsumura & Co.
4. Department of Surgery, Kochi Medical School Hospital
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/45/1/45_b21-00658/_pdf
Reference46 articles.
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2. 2) Shreiner AB, Kao JY, Young VB. The gut microbiome in health and in disease. Curr. Opin. Gastroenterol., 31, 69–75 (2015).
3. 3) Zhang J, Zhang J, Wang R. Gut microbiota modulates drug pharmacokinetics. Drug Metab. Rev., 50, 357–368 (2018).
4. 4) Zimmermann M, Zimmermann-Kogadeeva M, Wegmann R, Goodman AL. Mapping human microbiome drug metabolism by gut bacteria and their genes. Nature, 570, 462–467 (2019).
5. 5) Kobashi K, Akao T. Relation of intestinal bacteria to pharmacological effects of glycosides. Biosci. Microflora, 16, 1–7 (1997).
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