Structure Activity Relationships of Quinoxalin-2-one Derivatives as Platelet-Derived Growth Factor-.BETA. Receptor (PDGF.BETA. R) Inhibitors, Derived from Molecular Modeling-Reference-Cited by-同舟云学术

Structure Activity Relationships of Quinoxalin-2-one Derivatives as Platelet-Derived Growth Factor-.BETA. Receptor (PDGF.BETA. R) Inhibitors, Derived from Molecular Modeling

Published:2008 Issue:5 Volume:56 Page:682-687
ISSN:0009-2363
Container-title:Chemical and Pharmaceutical Bulletin
language:en
Short-container-title:CHEMICAL & PHARMACEUTICAL BULLETIN

Author:

Mori Yoshikazu¹²,Hirokawa Takatsugu³,Aoki Katsuyuki¹²,Satomi Hisanori¹,Takeda Shuichi¹,Aburada Masaki⁴,Miyamoto Ken-ichi²

Affiliation:

1. R & D Division, Tsumura & Co.

2. Department of Clinical Pharmacy, Graduate School of Natural Science and Technology, Kanazawa University

3. Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology

4. Research Institute of Pharmaceutical Sciences, Musashino University

Publisher

Pharmaceutical Society of Japan

Subject

Drug Discovery,General Chemistry,General Medicine

Link

http://www.jstage.jst.go.jp/article/cpb/56/5/56_5_682/_pdf

Reference47 articles.

1. The Protein Kinase Complement of the Human Genome

2. PDGF receptors as cancer drug targets

3. Attachment of smooth muscle cells to collagen and their migration toward platelet-derived growth factor.

4. Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization.

5. Localization of PDGF-B Protein in Macrophages in All Phases of Atherogenesis

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