Spermine Moiety Attached to the C-5 Position of Deoxyuridine Enhances the Duplex Stability of the Phosphorothioate DNA/Complementary DNA and Shows the Susceptibility of the Substrate to RNase H
Author:
Affiliation:
1. Graduate School of Engineering, Gunma University
Publisher
Pharmaceutical Society of Japan
Subject
Drug Discovery,General Chemistry,General Medicine
Link
http://www.jstage.jst.go.jp/article/cpb/56/9/56_9_1259/_pdf
Reference43 articles.
1. Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H
2. Antisense Gene Inhibition by Oligonucleotides Containing C-5 Propyne Pyrimidines
3. Phosphorothioate Oligodeoxynucleotides: What Is Their Origin and What Is Unique About Them?
4. Long-Range Cooperativity in Molecular Recognition of RNA by Oligodeoxynucleotides with Multiple C5-(1-Propynyl) Pyrimidines
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3. Post-synthetic modification of oligonucleotides containing 5-mono- and 5-di-fluoromethyluridines;Tetrahedron;2021-01
4. Construction of Pyrimidine Bases Bearing Carboxylic Acid Equivalents at the C5 Position by Postsynthetic Modification of Oligonucleotides;Current Protocols in Nucleic Acid Chemistry;2019-07-03
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