Pharmacokinetic and Pharmacodynamic Evaluation of the Anti-cataract Effect of Eye Drops Containing Disulfiram and Low-Substituted Methylcellulose Using ICR/f Rats as a Hereditary Cataract Model

Author:

Nagai Noriaki1,Ito Yoshimasa12,Takeuchi Noriko3

Affiliation:

1. Faculty of Pharmacy, Kinki University

2. Pharmaceutical Research and Technology Institute, Kinki University

3. Section of Biochemistry, Faculty of Pharmacy, Meijo University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference35 articles.

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2. 2) Iwata S. Suisyoutai (Crystalline lens), Chap. 7, (Iwata S ed.) Medical-Aoi Publication, Tokyo, pp. 355—360 (1986).

3. Role of site-specific, metal-catalyzed oxidation in lens aging and cataract: A hypothesis

4. 4) Rasi V, Costantini S, Moramarco A, Giordano R, Giustolisi R, Balacco Gabrieli C. Inorganic element concentrations in cataractous human lenses. Ann. Ophthalmol., 24, 459—464 (1992).

5. Lenticular Calcium, Magnesium, and Iron Levels in Diabetic Rats and Verapamil Effect

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