1. 1) Abbreviations used are as follows: All amino acids are of the L-configuration. AcOH, acetic acid; AcONH4, ammonium acetate; Ac2O, acetic anhydride; Boc, tert-butoxycarbonyl; tBu, tert-butyl; CCK, cholecystokinin; Clt resin, 2-chlorotrityl chloride resin; DIPCDI, N,N-diisopropylcarbodiimide; DKP, diketopiperazine; Fmoc, fluoren-9-yl-methoxycarbonyl; G34-II, human big gastrin-II; G34-Gly sulfate, C-terminal glycine-extended big gastrin sulfate; HFIP, hexafluoro-2-propanol; HOBt, N-hydroxybenzotriazole; HOOBt, 3,4-dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine; LSIMS, liquid secondary-ion mass spectrometry; NMM, N-methylmorpholine; Pfp, pentafluorophenyl; PyBOP, benzotriazolyloxytris(pyrrolidino)phosphonium hexafluorophosphate; SPPS, solid-phase peptide synthesis; Su, N-hydroxysuccinimidyl; TFE, 2,2,2-trifluoroethanol; TFA, trifluoroacetic acid.
2. Facile Solid-Phase Synthesis of Sulfated Tyrosine-Containing Peptides: Total Synthesis of Human Big Gastrin-II and Cholecystokinin (CCK)-391,2
3. 3) Solution-phase; a) Moroder L., Wünsch E., “Natural Product Chemistry,” Vol. 26, ed. by Attr-ur-Rahman, Springer Verlag, Berlin, 1986, pp. 255-280 and references cited therein
4. Synthesis of cholecystokinin-pancreozymin. I. C-terminal dodecapeptide