Stereoselective Metabolism of Racemic Carvedilol by UGT1A1 and UGT2B7, and Effects of Mutation of these Enzymes on Glucuronidation Activity-Reference-Cited by-同舟云学术

Stereoselective Metabolism of Racemic Carvedilol by UGT1A1 and UGT2B7, and Effects of Mutation of these Enzymes on Glucuronidation Activity

Published:2007 Issue:11 Volume:30 Page:2146-2153
ISSN:0918-6158
Container-title:Biological and Pharmaceutical Bulletin
language:en
Short-container-title:Biol. Pharm. Bull.

Author:

Takekuma Yoh¹,Takenaka Toru²,Yamazaki Koujiro²,Ueno Kazuyuki³,Sugawara Mitsuru²

Affiliation:

1. Laboratory of Pharmcotherapeutic Information, Department of Biopharmaceutical Sciences and Pharmacy, Faculty of Pharmaceutical Sciences, Hokkaido University

2. Department of Pharmacy, Hokkaido University Hospital

3. Department of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

http://www.jstage.jst.go.jp/article/bpb/30/11/30_11_2146/_pdf

Reference33 articles.

1. Clinical pharmacologic investigations with carvedilol, a new beta-blocker with direct vasodilator activity

2. Carvedilol

3. The Effect of Carvedilol on Morbidity and Mortality in Patients with Chronic Heart Failure

4. Carvedilol increases two-year survivalin dialysis patients with dilated cardiomyopathy

5. Carvedilol

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