Quercetin-3-O-α-L-arabinopyranosyl-(1→2)-β-D-glucopyranoside Isolated from Eucommia ulmoides Leaf Relieves Insulin Resistance in HepG2 Cells via the IRS-1/PI3K/Akt/GSK-3β Pathway-Reference-Cited by-同舟云学术

Quercetin-3-O-α-L-arabinopyranosyl-(1→2)-β-D-glucopyranoside Isolated from Eucommia ulmoides Leaf Relieves Insulin Resistance in HepG2 Cells via the IRS-1/PI3K/Akt/GSK-3β Pathway

Published:2023-02-01 Issue:2 Volume:46 Page:219-229
ISSN:0918-6158
Container-title:Biological and Pharmaceutical Bulletin
language:en
Short-container-title:Biological & Pharmaceutical Bulletin

Author:

Tang Peng¹,Tang Yong²,Liu Yan³,He Bing⁴,Shen Xin⁵,Zhang Zhi-Jie⁴,Qin Da-Lian⁴,Tian Ji⁴

Affiliation:

1. Clinical Medical College & Affiliated Hospital of Chengdu University

2. State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology

3. Drug Discovery Research Center of Southwest Medical University

4. School of Pharmacy, Southwest Medical University

5. Sichuan Key Laboratory of New Drug Discovery and Druggability Evaluation, Luzhou Key Laboratory of Bioactivity Screening in Traditional Chinese Medicine and Druggability Evalution, School of Pharmacy, Southwest Medical University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

https://www.jstage.jst.go.jp/article/bpb/46/2/46_b22-00597/_pdf

Reference59 articles.

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3. 3) Ashcroft FM, Rorsman P. Diabetes mellitus and the β cell: the last ten years. Cell, 148, 1160–1171 (2012).

4. 4) Zhang Y, Yan LS, Ding Y, Cheng BC, Luo G, Kong J, Liu TH, Zhang SF. Edgeworthia gardneri (Wall.) Meisn. water extract ameliorates palmitate induced insulin resistance by regulating IRS1/GSK3β/FoxO1 signaling pathway in human HepG2 hepatocytes. Front. Pharmacol., 10, 1666 (2020).

5. 5) Yang XP, Li LL, Fang K, Dong RL, Li JB, Zhao Y, Dong H, Yi P, Huang ZY, Chen G, Lu F. Wu-Mei-Wan reduces insulin resistance via inhibition of NLRP3 inflammasome activation in HepG2 cells. Evid. Based Complement. Alternat. Med., 2017, 7283241 (2017).

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