Negative Inotropic Effects of Class I Antiarrhythmics on Guinea Pig Ventricular Myocardium: Correlation with L-Type Ca<sup>2+</sup> Channel Blockade
Author:
Affiliation:
1. Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/46/1/46_b22-00644/_pdf
Reference15 articles.
1. 1) Lei M, Wu L, Terrar DA, Huang CL. Modernized classification of cardiac antiarrhythmic drugs. Circulation, 138, 1879–1896 (2018).
2. 2) Nawada T, Tanaka Y, Hirai S, Hisatome I, Hasegawa J, Kotake H, Mashiba H. Evaluation of negative inotropic and antiarrhythmic effects of class 1 antiarrhythmic drugs. Int. J. Clin. Pharmacol. Ther., 32, 347–355 (1994).
3. 3) JCS Joint Working Group. Guidelines for Pharmacotherapy of Atrial Fibrillation (JCS 2013). Circ. J., 78, 1997–2021 (2014).
4. 4) Irie M, Hiiro H, Hamaguchi S, Namekata I, Tanaka H. Involvement of the persistent Na+ current in the diastolic depolarization and automaticity of the guinea pig pulmonary vein myocardium. J. Pharmacol. Sci., 141, 9–16 (2019).
5. 5) Hamaguchi S, Kariya M, Ozaki AF, Namekata I, Tanaka H. Contribution of ATP-mediated positive feedback to sympathetic nerve-induced positive inotropy in Guinea pig ventricular myocardium. Biol. Pharm. Bull., 44, 458–460 (2021).
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