Estimation of the Viscosity of an Antibody Solution from the Diffusion Interaction Parameter
Author:
Affiliation:
1. Department of Pharmaceutical Technology, Astellas Pharma Inc.
2. Department of Biotechnology, Graduate School of Engineering, Osaka University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/45/9/45_b22-00263/_pdf
Reference44 articles.
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3. 3) Kohli N, Jain N, Geddie ML, Razlog M, Xu L, Lugovskoy AA. A novel screening method to assess developability of antibody-like molecules. MAbs, 7, 752–758 (2015).
4. 4) Lipinski CA, Lombardo F, Dominy BW, Feeney PJ. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev., 46, 3–26 (2001).
5. 5) Jain T, Sun T, Durand S, Hall A, Houston NR, Nett JH, Sharkey B, Bobrowicz B, Caffry I, Yu Y, Cao Y, Lynaugh H, Brown M, Baruah H, Gray LT, Krauland EM, Xu Y, Vásquez M, Wittrup KD. Biophysical properties of the clinical-stage antibody landscape. Proc. Natl. Acad. Sci. U.S.A., 114, 944–949 (2017).
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