Ibudilast Reduces IL-6 Levels and Ameliorates Symptoms in Lipopolysaccharide-Induced Sepsis Mice
Author:
Affiliation:
1. Department of Pharmaceutical Pharmacology, College of Pharmaceutical Sciences, Matsuyama University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/45/8/45_b22-00284/_pdf
Reference30 articles.
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2. 2) Gaieski DF, Edwards JM, Kallan MJ, Carr BG. Benchmarking the incidence and mortality of severe sepsis in the United States. Crit. Care Med., 41, 1167–1174 (2013).
3. 3) Cohen J, Opal S, Calandra T. Sepsis studies need new direction. Lancet Infect. Dis., 12, 503–505 (2012).
4. 4) Savva A, Roger T. Targeting Toll-like receptors: promising therapeutic strategies for the management of sepsis-associated pathology and infectious diseases. Front. Immunol., 4, 387 (2013).
5. 5) Fink MP, Warren HS. Strategies to improve drug development for sepsis. Nat. Rev. Drug Discov., 13, 741–758 (2014).
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