Design and Synthesis of Peptidomimetic Factor VIIa Inhibitors
Author:
Affiliation:
1. Fuji Gotemba Research Laboratories, Chugai Pharmaceutical Co., Ltd.
Publisher
Pharmaceutical Society of Japan
Subject
Drug Discovery,General Chemistry,General Medicine
Link
http://www.jstage.jst.go.jp/article/cpb/58/1/58_1_38/_pdf
Reference29 articles.
1. The coagulation cascade: initiation, maintenance, and regulation
2. Redefining medical treatment in the management of unstable angina
3. Inhibition of Arterial Thrombosis by a Soluble Tissue Factor Mutant and Active Site-blocked Factors IXa and Xa in the Guinea Pig
4. Pharmacological Interruption of Acute Thrombus Formation with Minimal Hemorrhagic Complications by a Small Molecule Tissue Factor/Factor VIIa Inhibitor: Comparison to Factor Xa and Thrombin Inhibition in a Nonhuman Primate Thrombosis Model
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1. Structural model of tissue factor (TF) and TF-factor VIIa complex in a lipid membrane: A combined experimental and computational study;Journal of Colloid and Interface Science;2022-10
2. Ligand Induced Conformational Transitions of Tissue Factor Omega Loop;CHINESE J STRUC CHEM;2018
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