Human Induced Pluripotent Stem Cell-Based Skin for Assessing Transdermal Drug Permeability and Irritancy
Author:
Affiliation:
1. Department of Biopharmaceutics, Kyoto Pharmaceutical University
2. Laboratory of Stem Cell Regulation, National Institutes of Biomedical Innovation, Health and Nutrition
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/44/1/44_b20-00587/_pdf
Reference22 articles.
1. 1) Todo H, Oshizaka T, Kadhum WR, Sugibayashi K. Mathematical model to predict skin concentration after topical application of drugs. Pharmaceutics, 5, 634-651 (2013).
2. 2) Uchida T, Kadhum WR, Kanai S, Todo H, Oshizaka T, Sugibayashi K. Prediction of skin permeation by chemical compounds using the artificial membrane, Strat-M™. Eur. J. Pharm. Sci., 67, 113–118 (2015).
3. 3) Naito C, Yamaguchi T, Katsumi H, Kimura S, Kamei S, Morishita M, Sakane T, Kawabata K, Yamamoto A. Utility of three-dimensional skin from human-induced pluripotent stem cells as a tool to evaluate transdermal drug permeation. J. Pharm. Sci., 108, 3524–3527 (2019).
4. 4) Itoh M, Kiuru M, Cairo MS, Christiano AM. Generation of keratinocytes from normal and recessive dystrophic epidermolysis bullosa-induced pluripotent stem cells. Proc. Natl. Acad. Sci. U.S.A., 108, 8797–8802 (2011).
5. 5) Petrova A, Celli A, Jacquet L, Dafou D, Crumrine D, Hupe M, Arno M, Hobbs C, Cvoro A, Karagiannis P, Devito L, Sun R, Adame LC, Vaughan R, McGrath JA, Mauro TM, Ilic D. 3D in vitro model of a functional epidermal permeability barrier from human embryonic stem cells and induced pluripotent stem cells. Stem Cell Reports, 2, 675–689 (2014).
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