Binding Affinity of a Newly Synthesized 5-HT2 Antagonist, AT-1015 (N-[2-[4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-piperidino]ethyl]-1-formyl-4-piperidinecarboxamide Monohydrochloride Monohydrate), in the Rabbit Platelet Membrane.-Reference-Cited by-同舟云学术

Binding Affinity of a Newly Synthesized 5-HT2 Antagonist, AT-1015 (N-[2-[4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-piperidino]ethyl]-1-formyl-4-piperidinecarboxamide Monohydrochloride Monohydrate), in the Rabbit Platelet Membrane.

Published:2001 Issue:10 Volume:24 Page:1188-1190
ISSN:0918-6158
Container-title:Biological and Pharmaceutical Bulletin
language:en
Short-container-title:Biol. Pharm. Bull.

Author:

RASHID Mamunur¹,WATANABE Masatomo²,NAKAZAWA Mikio³,NAGATOMO Takafumi¹

Affiliation:

1. Department of Pharmacology, Niigata College of Pharmacy

2. Department of Public Health, Niigata College of Medical Technology

3. Department of Medical Technology, School of Health Sciences, Faculty of Medicine, Niigata University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

http://www.jstage.jst.go.jp/article/bpb/24/10/24_10_1188/_pdf

Reference15 articles.

1. Evidence for functional 5-HT2 receptor sites on human blood platelets

2. Platelet-mediated vascular permeability in the rat: A predominant role for 5-hydroxytryptamine

3. Stimulation of aortic smooth muscle cell mitogenesis by serotonin.

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1. Identification of Amino Acid Residues Important for Sarpogrelate Binding to the Human 5-Hydroxytryptamine2A Serotonin Receptor;Journal of Pharmacological Sciences;2006

2. Functions of 5-HT2A receptor and its antagonists in the cardiovascular system;Pharmacology & Therapeutics;2004-10

3. AT-1015, a newly synthesized 5-HT2 receptor antagonist, dissociates slowly from the 5-HT2 receptor sites in rabbit cerebral cortex membrane;Journal of Pharmacy and Pharmacology;2002-08