Hair Analysis for Pharmaceutical Drugs. II. Effective Extraction and Determination of Sildenafil (Viagra) and Its N-Desmethyl Metabolite in Rat and Human Hair by GC-MS.
Author:
Affiliation:
1. National Institute of Health Sciences
2. Kishiwada City Hospital
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
http://www.jstage.jst.go.jp/article/bpb/24/12/24_12_1384/_pdf
Reference10 articles.
1. 1) This work was presented at the Annual Meeting of the Pharmaceutical Sciences of Japan at Sapporo in 2001.
2. Hair Analysis for Pharmaceutical Drugs. I. Effective Extraction and Determination of Phenobarbital, Phenytoin and Their Major Metabolites in Rat and Human Hair.
3. 3) http://www.fda.gov/cder/consumerinfo/viagra/viagraupdate721.htm, July 22 (1998).
4. Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man
5. Development of an assay for the simultaneous determination of sildenfail (viagra) and its metabolite (UK-103,320) using automated sequential trace enrichment of dialysates and high-performance liquid chromatography
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