Direct <i>N</i><sup>1</sup>-Selective Alkylation of Hydantoins Using Potassium Bases-Reference-Cited by-同舟云学术

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Direct N¹-Selective Alkylation of Hydantoins Using Potassium Bases

Published:2021-04-01 Issue:4 Volume:69 Page:407-410
ISSN:0009-2363
Container-title:Chemical and Pharmaceutical Bulletin
language:en
Short-container-title:CHEMICAL & PHARMACEUTICAL BULLETIN

Author:

Shintani Yumi¹,Kato Koichi²,Kawami Masashi³,Takano Mikihisa³,Kumamoto Takuya¹

Affiliation:

1. Department of Synthetic Organic Chemistry, Graduate School of Biomedical and Health Sciences, Hiroshima University

2. Integrative Brain Imaging Center, National Center of Neurology and Psychiatry

3. Department of Pharmaceutics and Therapeutics, Graduate School of Biomedical and Health Sciences, Hiroshima University

Publisher

Pharmaceutical Society of Japan

Subject

Drug Discovery,General Chemistry,General Medicine

Link

https://www.jstage.jst.go.jp/article/cpb/69/4/69_c20-00857/_pdf

Reference29 articles.

1. 1) Meusel M., Gütschow M., Org. Prep. Proced. Int., 36, 391–443 (2004).

2. 2) Konnert L., Lamaty F., Martinez J., Colacino E., Chem. Rev., 117, 13757–13809 (2017).

3. 3) As report regarding efflux of phenytoin by P-gp, antiepileptic effect of phenytoin (1a) toward P-gp was effectively increased by coadministration of P-gp inhibitors tariquidar using the electrical post-status epilepticus rat model: Van Vliet E. A., Van Schaik R., Edelbroek P. M., Redeker S., Aronica E., Wadman W. J., Marchi N., Vezzani A., Gorter J. A., Epilepsia, 47, 672–680 (2006).

4. 4) It is also reported that intracellular accumulation of phenytoin (1a) in bovine retinal endothelial cells was not affected by P-gp inhibitors verapamil and PGP-4008: Maines L. W., Antonetti D. A., Wolpert E. B., Smith C. D., Neuropharmacology, 49, 610–617 (2005).

5. 5) Aller S. G., Yu J., Ward A., Weng Y., Chittaboina S., Zhuo R., Harrell P. M., Trinh Y. T., Zhang Q., Urbatsch I. L., Chang G., Science, 323, 1718–1722 (2009).

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. ROS/Electro Dual-Reactive Nanogel for Targeting Epileptic Foci to Remodel Aberrant Circuits and Inflammatory Microenvironment;ACS Nano;2023-04-11

2. Synthesis of new 5-benzylidene-hydantoin esters;Journal of Chemical Research;2022-07

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