Polymer Combination Increased Both Physical Stability and Oral Absorption of Solid Dispersions Containing a Low Glass Transition Temperature Drug: Physicochemical Characterization and <i>in Vivo</i> Study-Reference-Cited by-同舟云学术

Polymer Combination Increased Both Physical Stability and Oral Absorption of Solid Dispersions Containing a Low Glass Transition Temperature Drug: Physicochemical Characterization and in Vivo Study

Published:2012 Issue:4 Volume:60 Page:459-464
ISSN:0009-2363
Container-title:Chemical and Pharmaceutical Bulletin
language:en
Short-container-title:CHEMICAL & PHARMACEUTICAL BULLETIN

Author:

Sakurai Atsushi¹²,Sakai Toshiro¹,Sako Kazuhiro¹,Maitani Yoshie²

Affiliation:

1. Pharmaceutical Research and Technology Labs, Astellas Pharma Inc.

2. Institute of Medicinal Chemistry, Hoshi University

Publisher

Pharmaceutical Society of Japan

Subject

Drug Discovery,General Chemistry,General Medicine

Link

https://www.jstage.jst.go.jp/article/cpb/60/4/60_4_459/_pdf

Reference26 articles.

1. Pharmaceutical Applications of Solid Dispersion Systems

2. Solid dispersion of poorly water‐soluble drugs: Early promises, subsequent problems, and recent breakthroughs

3. Improving drug solubility for oral delivery using solid dispersions

4. Enhancement of dissolution of glyburide by solid dispersion and lyophilization techniques

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