Chemical Modification of Coumarin Dimer and HIV-1 Integrase Inhibitory Activity.
Author:
Affiliation:
1. Department of Pharmacy, Veterans General Hospital Kaohsiung
2. School of Pharmacy, National Defense Medical Center
3. L.B.P.A, CNRS UMR8532, Ecole Normale Superieure de Cachan
Publisher
Pharmaceutical Society of Japan
Subject
Drug Discovery,General Chemistry,General Medicine
Link
http://www.jstage.jst.go.jp/article/cpb/50/12/50_12_1634/_pdf
Reference19 articles.
1. Retroviral integrases and their cousins
2. Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules.
3. Integrase mutants of human immunodeficiency virus type 1 with a specific defect in integration
4. Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells
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