Pyroglutamyl Aminopeptidase I, as a Drug Metabolizing Enzyme, Recognizes Xenobiotic Substrates Containing L-2-Oxothiazolidine-4-carboxylic Acid
Author:
Affiliation:
1. Drug Metabolism and Pharmacokinetics Research Laboratories, Sankyo Co., Ltd.
2. Chemtech Labo., Inc.
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
http://www.jstage.jst.go.jp/article/bpb/27/1/27_1_113/_pdf
Reference17 articles.
1. 1) McDonald J. K., Barrett A. J., “Mammalian Proteases: A Glossary and Bibliography,” Vol. 2, Academic Press, London, 1986.
2. Bovine brain pyroglutamyl aminopeptidase (type-1): Purification and characterisation of a neuropeptide-inactivating peptidase
3. Pyroglutamyl peptidase from chicken liver: Purification and some properties.
4. Hydrolysis of Synthetic Substrate, L-Pyroglutamyl p-Nitroanilide is Catalyzed Solely by Pyroglutamyl Aminopeptidase I in Rat Liver Cytosol
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