Synthesis of 2-N,N-Dimethylaminomethyl-2,3,3a,12b-tetrahydrodibenzo-[b,f]furo[2,3-d]oxepin Derivatives as Potential Anxiolytic Agents-Reference-Cited by-同舟云学术

Synthesis of 2-N,N-Dimethylaminomethyl-2,3,3a,12b-tetrahydrodibenzo-[b,f]furo[2,3-d]oxepin Derivatives as Potential Anxiolytic Agents

Published:2004 Issue:2 Volume:52 Page:262-265
ISSN:0009-2363
Container-title:Chemical and Pharmaceutical Bulletin
language:en
Short-container-title:CHEMICAL & PHARMACEUTICAL BULLETIN

Author:

Trabanco Andrés Avelino¹,Alonso José Manuel¹,Andrés José Ignacio¹,Cid José Maria¹,Fernández Javier¹,Iturrino Laura¹,Megens Anton²

Affiliation:

1. Johnson & Johnson Pharmaceutical Research & Development, a Division of Janssen-Cilag S.A.

2. Johnson & Johnson Pharmaceutical Research & Development, a Division of Janssen Pharmaceutica N. V.

Publisher

Pharmaceutical Society of Japan

Subject

Drug Discovery,General Chemistry,General Medicine

Link

http://www.jstage.jst.go.jp/article/cpb/52/2/52_2_262/_pdf

Reference21 articles.

1. Synthesis and structure–activity relationship of 2-(aminoalkyl)-2,3,3a,8-tetrahydrodibenzo[c,f]isoxazolo[2,3-a]azepine derivatives: a novel series of 5-HT2A/2C receptor antagonists. Part 1

2. Synthesis and structure–Activity relationship of 2-(aminoalkyl)-2,3,3a,8-tetrahydrodibenzo[c,f]isoxazolo[2,3-a]azepine derivatives: a novel series of 5-HT2A/2C receptor antagonists. Part 2

3. 2-(Dimethylaminomethyl)-tetrahydroisoxazolopyridobenzazepine derivatives. Synthesis of a new 5-HT2C antagonist with potential anxiolytic properties

4. 4) Gil-Lopetegui P., Fernández-Gadea F. J., Meert T. F., Janssen Pharmaceutica N. V. Patent Application PCT/EP97/01829; WO 97/38991, 23 October, 1997.

5. 5) Andrés-Gil J. I., Fernández-Gadea F. J., Gil-Lopetegui P., Díaz-Martínez A., Janssen Pharmaceutica N. V. Patent Application PCT/EP98/06352; WO 99/19317, 22 April, 1999.

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