A New Hypoxia Inducible Factor-2 Inhibitory Pyrrolinone Alkaloid from Roots and Stems of Piper sarmentosum
Author:
Affiliation:
1. SAIC-Frederick, Inc.
2. Molecular Targets Laboratory, Center for Cancer Research
3. Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, U.S.A
Publisher
Pharmaceutical Society of Japan
Subject
Drug Discovery,General Chemistry,General Medicine
Link
http://www.jstage.jst.go.jp/article/cpb/59/9/59_9_1178/_pdf
Reference13 articles.
1. Role of Hypoxia-Inducible Factor (HIF)-1α versus HIF-2α in the Regulation of HIF Target Genes in Response to Hypoxia, Insulin-Like Growth Factor-I, or Loss of von Hippel-Lindau Function: Implications for Targeting the HIF Pathway
2. Identification of the Genes for Kidney Cancer: Opportunity for Disease-Specific Targeted Therapeutics
3. Targeting hypoxia cell signaling for cancer therapy
4. Development of a Cell-Based Reporter Assay for Screening of Inhibitors of Hypoxia-Inducible Factor 2-Induced Gene Expression
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