Loss of Mitochondrial DNA by Gemcitabine Triggers Mitophagy and Cell Death
Author:
Affiliation:
1. Division of Life Science, Department of Pharmacy, Hokkaido University of Science
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/42/12/42_b19-00312/_pdf
Reference64 articles.
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3. 3) Paproski RJ, Young JD, Cass CE. Predicting gemcitabine transport and toxicity in human pancreatic cancer cell lines with the positron emission tomography tracer 3′-deoxy-3′-fluorothymidine. Biochem. Pharmacol., 79, 587–595 (2010).
4. 4) Engelke CG, Parsels LA, Qian Y, Zhang Q, Karnak D, Robertson JR, Tanska DM, Wei D, Davis MA, Parsels JD, Zhao L, Greenson JK, Lawrence TS, Maybaum J, Morgan MA. Sensitization of pancreatic cancer to chemoradiation by the Chk1 inhibitor MK8776. Clin. Cancer Res., 19, 4412–4421 (2013).
5. 5) Ikura T, Ogryzko VV, Grigoriev M, Groisman R, Wang J, Horikoshi M, Scully R, Qin J, Nakatani Y. Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell, 102, 463–473 (2000).
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