Association of Initial Trough Concentrations of Vancomycin with Outcomes in Pediatric Patients with Gram-Positive Bacterial Infection

Author:

Kondo Miko1,Nakagawa Shunsaku1,Orii Satoru1,Itohara Kotaro1,Sugimoto Mitsuhiro1,Omura Tomohiro2,Sato Yuki1,Imai Satoshi1,Yonezawa Atsushi13,Nakagawa Takayuki1,Matsubara Kazuo1

Affiliation:

1. Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital

2. Department of Pharmacy, Kobe University Hospital

3. Graduate School of Pharmaceutical Sciences, Kyoto University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference34 articles.

1. 1) Liu C, Bayer A, Cosgrove SE, Daum RS, Fridkin SK, Gorwitz RJ, Kaplan SL, Karchmer AW, Levine DP, Murray BEJ, J Rybak M, Talan DA, Chambers HF. Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. Clin. Infect. Dis., 52, e18–e55 (2011).

2. 2) Yasuhara M, Iga T, Zenda H, Okumura K, Oguma T, Yano Y, Hori R. Population pharmacokinetics of vancomycin in Japanese pediatric patients. Ther. Drug Monit., 20, 612–618 (1998).

3. 3) Monteiro JF, Hahn SR, Gonçalves J, Fresco P. Vancomycin therapeutic drug monitoring and population pharmacokinetic models in special patient subpopulations. Pharmacol. Res. Perspect., 6, e00420 (2018).

4. 4) Rybak MJ, Le J, Lodise TP, Levine DP, Bradley JS, Liu C, Mueller BA, Pai MP, Wong-Beringer A, Rotschafer JC, Rodvold KA, Maples HD, Lomaestro BM. Executive summary: therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: a revised consensus guideline and review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists. Pharmacotherapy, 40, 363–367 (2020).

5. 5) McKamy S, Hernandez E, Jahng M, Moriwaki T, Deveikis A, Le J. Incidence and risk factors influencing the development of vancomycin nephrotoxicity in children. J. Pediatr., 158, 422–426 (2011).

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