Postoperative Anaemia Is a Risk Factor for Bleeding-Related Event in Thromboprophylaxis Using Fondaparinux Sodium Injection after Total Knee or Hip Arthroplasty

Author:

Enokiya Tomoyuki1,Hasegawa Masahiro2,Morikawa Yoshihiko1,Muraki Yuichi1,Sudo Akihiro2,Okuda Masahiro1

Affiliation:

1. Department of Pharmacy, Mie University Hospital, Mie University

2. Department of Orthopedic Surgery, Mie University Hospital, Mie University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference28 articles.

1. 1) Geerts WH, Heit JA, Clagett GP, Pineo GF, Colwell CW, Anderson FA Jr, Wheeler HB. Prevention of venous thromboembolism. Chest, 119 (Suppl.), 132S–175S (2001).

2. 2) Nicolaides AN, Breddin HK, Fareed J, Goldhaber S, Haas S, Hull R, Kalodiki E, Myers K, Samama M, Sasahara A. Prevention of venous thromboembolism. International Consensus Statement. Guidelines compiled in accordance with the scientific evidence. Int. Angiol., 20, 1–37 (2001).

3. 3) Bauer KA, Eriksson BI, Lassen MR, Turpie AG. Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after elective major knee surgery. N. Engl. J. Med., 345, 1305–1310 (2001).

4. 4) Lassen MR, Bauer KA, Eriksson BI, Turpie AG. Postoperative fondaparinux versus preoperative enoxaparin for prevention of venous thromboembolism in elective hip-replacement surgery: a randomised double-blind comparison. Lancet, 359, 1715–1720 (2002).

5. 5) Lormeau JC, Herault JP. The effect of the synthetic pentasaccharide SR 90107/ORG 31540 on thrombin generation ex vivo is uniquely due to ATIII-mediated neutralization of factor Xa. Thromb. Haemost., 74, 1474–1477 (1995).

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