The Anti-atherogenic Activity of Beauveriolide Derivative BVD327, a Sterol <i>O</i>-Acyltransferase 2-Selective Inhibitor, in Apolipoprotein E Knockout Mice-Reference-Cited by-同舟云学术

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The Anti-atherogenic Activity of Beauveriolide Derivative BVD327, a Sterol O-Acyltransferase 2-Selective Inhibitor, in Apolipoprotein E Knockout Mice

Published:2020-06-01 Issue:6 Volume:43 Page:951-958
ISSN:0918-6158
Container-title:Biological and Pharmaceutical Bulletin
language:en
Short-container-title:Biol. Pharm. Bull.

Author:

Ohshiro Taichi¹²,Imuta Satoshi³,Hijikuro Ichiro³,Yagyu Hiroaki⁴,Takahashi Takashi⁵,Doi Takayuki⁶,Ishibashi Shun⁴,Tomoda Hiroshi¹²

Affiliation:

1. Graduate School of Pharmaceutical Sciences, Kitasato University

2. Medicinal Research Laboratories, School of Pharmacy, Kitasato University

3. Tokyo Chemical Industry CO., LTD.

4. Division of Endocrinology and Metabolism, Department of Internal Medicine, School of Medicine, Jichi Medical University

5. Faculty of Pharmaceutical Sciences, Yokohama College of Pharmacy

6. Graduate School of Pharmaceutical Sciences, Tohoku University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

https://www.jstage.jst.go.jp/article/bpb/43/6/43_b19-00913/_pdf

Reference48 articles.

1. 1) Namatame I, Tomoda H, Si S, Yamaguchi Y, Masuma R, Omura S. Beauveriolides, specific inhibitors of lipid droplet formation in mouse macrophages, produced by Beauveria sp. FO-6979. J. Antibiot., 52, 1–6 (1999).

2. 2) Namatame I, Tomoda H, Tabata N, Si S, Omura S. Structure elucidation of fungal beauveriolide III, a novel inhibitor of lipid droplet formation in mouse macrophages. J. Antibiot., 52, 7–12 (1999).

3. 3) Mochizuki K, Ohmori K, Tamura H, Shizuri Y, Nishiyama S, Miyoshi E, Yamamura S. The structures of bioactive cyclodepsipeptides, beauveriolides I and II, Metabolites of entomopathogenic fungi beauveria sp. Bull. Chem. Soc. Jpn., 66, 3041–3046 (1993).

4. 4) Namatame I, Tomoda H, Ishibashi S, Omura S. Antiatherogenic activity of fungal beauveriolides, inhibitors of lipid droplet accumulation in macrophages. Proc. Natl. Acad. Sci. U.S.A., 101, 737–742 (2004).

5. 5) Tomoda H, Doi T. Discovery and combinatorial synthesis of fungal metabolites beauveriolides, novel antiatherosclerotic agents. Acc. Chem. Res., 41, 32–39 (2008).

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