Schizandrin B Mitigates Rifampicin-Induced Liver Injury by Inhibiting Endoplasmic Reticulum Stress
Author:
Affiliation:
1. Nanjing University of Chinese Medicine
2. Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University
3. The First Affiliated Hospital of Anhui University of Chinese Medicine
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/43/1/43_b19-00725/_pdf
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3. 3) Cano M, Wang L, Wan J, Barnett BP, Ebrahimi K, Qian J, Handa JT. Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in RPE cells. Free Radic. Biol. Med., 69, 1–14 (2014).
4. 4) Hassler JR, Scheuner DL, Wang S, Han J, Kodali VK, Li P, Nguyen J, George JS, Davis C, Wu SP, Bai Y, Sartor M, Cavalcoli J, Malhi H, Baudouin G, Zhang Y, Yates JI III, Itkin-Ansari P, Volkmann N, Kaufman RJ. The IRE1alpha/XBP1s pathway is essential for the glucose response and protection of beta cells. PLOS Biol., 13, e1002277 (2015).
5. 5) Ghosh R, Wang L, Wang ES, et al. Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress. Cell, 158, 534–548 (2014).
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