The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice

Author:

Okuda Michiaki12,Fujita Yuki12,Sugimoto Hachiro3

Affiliation:

1. Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University

2. Green Tech Co., Ltd.

3. Faculty of Life and Medical Sciences, Doshisha University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference135 articles.

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2. 2) Wischik CM, Novak M, Thøgersen HC, Edwards PC, Runswick MJ, Jakes R, Walker JE, Milstein C, Roth M, Klug A. Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A., 85, 4506–4510 (1988).

3. 3) Choi DY, Lee YJ, Hong JT, Lee HJ. Antioxidant properties of natural polyphenols and their therapeutic potentials for Alzheimer’s disease. Brain Res. Bull., 87, 144–153 (2012).

4. 4) Gómez-Pinilla F. Brain foods: the effects of nutrients on brain function. Nat. Rev. Neurosci., 9, 568–578 (2008).

5. 5) Ou S, Kwok K-C. Ferulic acid: pharmaceutical functions, preparation and applications in foods. J. Sci. Food Agric., 84, 1261–1269 (2004).

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