Design of a Novel PEGylated Liposomal Vector for Systemic Delivery of siRNA to Solid Tumors

Author:

Song Furan1,Sakurai Naoyuki1,Okamoto Ayaka1,Koide Hiroyuki1,Oku Naoto12,Dewa Takehisa3,Asai Tomohiro1

Affiliation:

1. Department of Medical Biochemistry, University of Shizuoka School of Pharmaceutical Sciences

2. Laboratory of Biomedical and Analytical Sciences, Faculty of Pharma Sciences, Teikyo University

3. Department of Life and Materials Engineering, Nagoya Institute of Technology

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference29 articles.

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3. 3) Hannon GJ. RNA interference. Nature, 418, 244–251 (2002).

4. 4) Diederichs S, Haber DA. Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression. Cell, 131, 1097–1108 (2007).

5. 5) Meister G, Landthaler M, Patkaniowska A, Dorsett Y, Teng G, Tuschl T. Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol. Cell, 15, 185–197 (2004).

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