Anti-proliferative Activities of Some Bivalent Symmetrical 5-Substituted Hydantoin Derivatives towards Human Brain Glioma U251 Cells (U251) and Human Carcinoma Cells (KB3-1)

Author:

Furutachi Makoto1,Ota Kaori1,Fujisaki Fumiko1,Ikeda Ryuji2,Yoshikawa Naoki2,Yokota Tsubasa2,Takeda Yasuo3,Yokomizo Kazumi4,Zhou Jian-Rong4,Kashige Nobuhiro1,Miake Fumio1,Sumoto Kunihiro1

Affiliation:

1. Faculty of Pharmaceutical Sciences, Fukuoka University

2. Department of Pharmacy, University of Miyazaki Hospital

3. Kagoshima University Hospital

4. Faculty of Pharmaceutical Sciences, Sojo University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference29 articles.

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2. 2) Oshovsky GV, Reinhoudt DN, Verboom W. Supramolecular chemistry in water. Angew. Chem. Int. Ed., 46, 2366–2393 (2007).

3. 3) Gibson SE, Castaldi MP. C3 symmetry: molecular design inspired by nature. Angew. Chem. Int. Ed., 45, 4718–4720 (2006).

4. 4) Bérubé G. Natural and synthetic biologically active dimeric molecules: anticancer agents, anti-HIV agents, steroid derivatives and opioid antagonists. Curr. Med. Chem., 13, 131–154 (2006).

5. 5) Micewicz ED, Luong HT, Jung C-L, Waring AJ, McBride WH, Ruchala P. Novel dimeric Smac analogs as prospective anticancer agents. Bioorg. Med. Chem. Lett., 24, 1452–1457 (2014).

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