Dendrobium officinale Attenuates Myocardial Fibrosis via Inhibiting EMT Signaling Pathway in HFD/STZ-Induced Diabetic Mice

Author:

Zeng Jie1,Li Dongning1,Li Zhubo1,Zhang Jie2,Zhao Xiaoyan1

Affiliation:

1. College of Pharmaceutical Sciences, Southwest University

2. Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference44 articles.

1. 1) Cho NH, Shaw JE, Karuranga S, Huang Y, da Rocha Fernandes JD, Ohlrogge AW, Malanda B. IDF diabetes atlas: global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes Res. Clin. Pract., 138, 271–281 (2018).

2. 2) DeFronzo RA. Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009. Diabetologia, 53, 1270–1287 (2010).

3. 3) Chen PH, Lin YK, Chang CK, Chiang SJ, Tsai SY. Dysregulation of glucose metabolism since young adulthood increases the risk of cardiovascular diseases in patients with bipolar disorder. Kaohsiung J. Med. Sci., 33, 630–636 (2017).

4. 4) Yan B, Singla DK. Transplanted induced pluripotent stem cells mitigate oxidative stress and improve cardiac function through the Akt cell survival pathway in diabetic cardiomyopathy. Mol. Pharm., 10, 3425–3432 (2013).

5. 5) Diao X, Shen E, Wang X, Hu B. Differentially expressed microRNAs and their target genes in the hearts of streptozotocin-induced diabetic mice. Mol. Med. Rep., 4, 633–640 (2011).

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