Analyses of Respiratory Depression Associated with Opioids in Cancer Patients Based on the Japanese Adverse Drug Event Report Database

Author:

Sugawara Hideki12,Uchida Mayako23,Suzuki Shinya24,Suga Yukio25,Uesawa Yoshihiro26,Nakagawa Takayuki27,Takase Hisamitsu28

Affiliation:

1. Department of Pharmacy, Kagoshima University Hospital

2. Research Promotion Committee, Japanese Society for Pharmaceutical Palliative Care and Sciences

3. Education and Research Center for Clinical Pharmacy, Osaka University of Pharmaceutical Sciences

4. Department of Pharmacy, National Cancer Center Hospital East

5. Department of Clinical Drug Informatics, Faculty of Pharmacy, Institute of Medical, Pharmaceutical & Health Science, Kanazawa University

6. Department of Medical Molecular Informatics, Meiji Pharmaceutical University

7. Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital

8. Nippon Medical School Tama-Nagayama Hospital

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference35 articles.

1. 1) Duthey B, Scholten W. Adequacy of opioid analgesic consumption at country, global, and regional levels in 2010, its relationship with development level, and changes compared with 2006. J. Pain Symptom Manage., 47, 283–297 (2014).

2. 2) Practice guidelines for the prevention, detection, and management of respiratory depression associated with neuraxial opioid administration: an updated report by the American Society of Anesthesiologists Task Force on Neuraxial Opioids and the American Society of Regional Anesthesia and Pain Medicine. Anesthesiology, 124, 535–552 (2016).

3. 3) Southern DA, Read MS. Overdosage of opiate from patient controlled analgesia devices. BMJ, 309, 1002 (1994).

4. 4) Cepeda MS, Farrar JT, Baumgarten M, Boston R, Carr DB, Strom BL. Side effects of opioids during short-term administration: effect of age, gender, and race. Clin. Pharmacol. Ther., 74, 102–112 (2003).

5. 5) Ostermeier AM, Roizen MF, Hautkappe M, Klock PA, Klafta JM. Three sudden postoperative respiratory arrests associated with epidural opioids in patients with sleep apnea. Anesth. Analg., 85, 452–460 (1997).

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