Enhancement of Warfarin Anticoagulant Reaction in Patients with Repeated Oral Tolvaptan Administration
Author:
Affiliation:
1. Department of Pharmacy, Tosei General Hospital
2. Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University
3. Department of Cardiovascular Medicine, Tosei General Hospital
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/41/7/41_b17-01008/_pdf
Reference8 articles.
1. 1) Kim SR, Hasunuma T, Sato O, Okada T, Kondo M, Azuma J. Pharmacokinetics, pharmacodynamics and safety of tolvaptan, a novel, oral, selective nonpeptide AVP V2-receptor antagonist: results of single- and multiple-dose studies in healthy Japanese male volunteers. Cardiovasc. Drugs Ther., 25 (Suppl. 1), S5–S17 (2011).
2. 2) Shoaf SE, Mallikaarjun S. Pharmacokinetic and pharmacodynamic interaction between tolvaptan and warfarin in healthy subjects. Clin. Pharmacol. Drug Dev., 1, 67–75 (2012).
3. 3) Karlson B, Leijd B, Hellström K. On the influence of vitamin K-rich vegetables and wine on the effectiveness of warfarin treatment. Acta Med. Scand., 220, 347–350 (1986).
4. 4) Clark NP, Delate T, Riggs CS, Witt DM, Hylek EM, Garcia DA, Ageno W, Dentali F, Crowther MA, Warfarin-Associated Research Projects and Other Endeavors Consortium. Warfarin interactions with antibiotics in the ambulatory care setting. JAMA Intern. Med., 174, 409–416 (2014).
5. 5) Vesell ES, Shively CA. Liquid chromatographic assay of warfarin: similarity of warfarin half-lives in human subjects. Science, 184, 466–468 (1974).
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1. Potential drug‐drug interaction between tolvaptan and warfarin in a geriatric patient with heart failure;Clinical Case Reports;2022-04
2. The Effect of Increased Free Concentrations of Warfarin Due to Protein-binding Substitution in a Combination of Tolvaptan on the PT-INR;YAKUGAKU ZASSHI;2020-10-01
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