Downregulation of Transcription Factor Sp1 Suppresses Malignant Properties of A549 Human Lung Cancer Cell Line with Decreased β4-Galactosylation of Highly Branched N-Glycans
Author:
Affiliation:
1. Laboratory of Glycobiology, Department of Bioengineering, Nagaoka University of Technology
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/40/8/40_b17-00212/_pdf
Reference45 articles.
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3. 3) Demetriou M, Nabi IR, Coppolino M, Dedhar S, Dennis JW. Reduced contact-inhibition and substratum adhesion in epithelial cells expressing GlcNAc-transferase V. J. Cell Biol., 130, 383–392 (1995).
4. 4) Asada M, Furukawa K, Segawa K, Endo T, Kobata A. Increased expression of highly branched N-glycans at cell surface is correlated with the malignant phenotypes of mouse tumor cells. Cancer Res., 57, 1073–1080 (1997).
5. 5) Granovsky M, Fata J, Pawling J, Muller WJ, Khokha R, Dennis JW. Suppression of tumor growth and metastasis in Mgat5-deficient mice. Nat. Med., 6, 306–312 (2000).
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