Study on the Increased Probability of Detecting Adverse Drug Reactions Based on Bayes’ Theorem: Evaluation of the Usefulness of Information on the Onset Timing of Adverse Drug Reactions

Author:

Oshima Shinji1,Enjuji Takako1,Negishi Akio1,Akimoto Hayato1,Ohara Kousuke2,Okita Mitsuyoshi3,Numajiri Sachihiko4,Inoue Naoko4,Ohshima Shigeru4,Terao Akira5,Kobayashi Daisuke1

Affiliation:

1. Department of Analytical Pharmaceutics and Informatics, Faculty of Pharmaceutical Sciences, Josai University

2. Laboratory of Drug Metabolism, Faculty of Pharmaceutical Sciences, Josai International University

3. Josai University Pharmacy

4. Laboratory of Pharmacy Management, Faculty of Pharmaceutical Sciences, Josai University

5. Laboratory of Biostatistics, Faculty of Pharmaceutical Sciences, Josai University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference16 articles.

1. 1) Oshima S, Senoo K, Negishi A, Akimoto H, Ohara K, Inoue N, Ohshima S, Kutsuma N, Juni K, Kobayashi D. Identification of the discrepancies between pharmacist and patient perception of the pharmacist’s role as an advisor on drug therapy based on social science theory. Biol. Pharm. Bull., 39, 313–322 (2016).

2. 2) Tsuchiya F. Revision of Pharmaceutical Affairs Law/Pharmacist Law, and providing patients with information on adverse drug reactions. Yakkyoku, 49, 1976–1982 (1998).

3. 3) Ohshima S, Ieda M, Yamamoto M, Kobayashi D. Quantitative evaluation method of information value of initial symptoms based on Bayesian theory. Yakugaku Zasshi, 132, 763–768 (2012).

4. 4) Kobayashi D, Hosaka S, Inoue E, Ohshima K, Kutsuma N, Oshima S, Okuno Y. Quantitative evaluation of initial symptoms as predictors to detect adverse drug reactions using Bayes’ theory: expansion and evaluation of drug-adverse drug reaction-initial symptom combinations using adverse event reporting system database. Biol. Pharm. Bull., 36, 1891–1901 (2013).

5. 5) Ghajar BM, Lanctôt KL, Shear NH, Naranjo CA. Bayesian differential diagnosis of a cutaneous reaction associated with the administration of sulfonamides. Semin. Dermatol., 8, 213–218 (1989).

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