Anti-cancer Effects of MW-03, a Novel Indole Compound, by Inducing 15-Hydroxyprostaglandin Dehydrogenase and Cellular Growth Inhibition in the LS174T Human Colon Cancer Cell Line-Reference-Cited by-同舟云学术

Anti-cancer Effects of MW-03, a Novel Indole Compound, by Inducing 15-Hydroxyprostaglandin Dehydrogenase and Cellular Growth Inhibition in the LS174T Human Colon Cancer Cell Line

Published:2017 Issue:10 Volume:40 Page:1806-1812
ISSN:0918-6158
Container-title:Biological & Pharmaceutical Bulletin
language:en
Short-container-title:Biol. Pharm. Bull.

Author:

Seira Naofumi¹,Yanagisawa Naoki¹,Suganami Akiko²,Honda Takuya³,Wasai Makiko⁴,Regan John W.⁵,Fukushima Keijo⁶,Yamaguchi Naoto³,Tamura Yutaka²,Arai Takayoshi⁴,Murayama Toshihiko¹,Fujino Hiromichi⁶

Affiliation:

1. Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University

2. Department of Bioinformatics, Graduate School of Medicine, Chiba University

3. Department of Molecular Cell Biology, Graduate School of Pharmaceutical Sciences, Chiba University

4. Department of Chemistry, Graduate School of Science, Chiba University

5. Department of Pharmacology and Toxicology, College of Pharmacy, The University of Arizona

6. Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences & Graduate School of Biomedical Sciences, Tokushima University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

https://www.jstage.jst.go.jp/article/bpb/40/10/40_b17-00458/_pdf

Reference31 articles.

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3. 3) Brown JR, DuBois J. COX-2: a molecular target for colorectal cancer prevention. J. Clin. Oncol., 23, 2840–2855 (2005).

4. 4) El-sayed MT, Hamdy NA, Osman DA, Ahmed KM. Indoles as anti-cancer agents. Adv. Mod. Oncol. Res., 1, 20–35 (2015).

5. 5) Ahmad A, Sakr WA, Rahman KM. Anticancer properties of indole compounds: mechanism of apoptosis induction and role in chemotherapy. Curr. Drug Targets, 11, 652–666 (2010).

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