Population Pharmacokinetics and Adverse Events of Erlotinib in Japanese Patients with Non-small-cell Lung Cancer: Impact of Genetic Polymorphisms in Metabolizing Enzymes and Transporters

Author:

Endo-Tsukude Chihiro123,Sasaki Ji-ichiro4,Saeki Sho5,Iwamoto Norihiro6,Inaba Megumi7,Ushijima Sunao7,Kishi Hiroto8,Fujii Shinji9,Semba Hiroshi9,Kashiwabara Kosuke10,Tsubata Yukari11,Hayashi Mitsuhiro2,Kai Yuki1,Saito Hideyuki15,Isobe Takeshi11,Kohrogi Hirotsugu1,Hamada Akinobu12

Affiliation:

1. Department of Medical Oncology and Translational Research, Graduate School of Pharmaceutical Sciences, Kumamoto University

2. National Cancer Center Research Institute

3. Chugai Pharmaceutical Co., Ltd.

4. Kitasato University Hospital

5. Kumamoto University Hospital

6. Saiseikai Kumamoto Hospital

7. Kumamoto Central Hospital

8. Kumamoto City Hospital

9. Kumamoto Regional Medical Center

10. Kumamoto Medical Center

11. Shimane University Hospital

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference53 articles.

1. 1) Shepherd FA, Rodrigues Pereira J, Ciuleanu T, Tan EH, Hirsh V, Thongprasert S, Campos D, Maoleekoonpiroj S, Smylie M, Martins R, van Kooten M, Dediu M, Findlay B, Tu D, Johnston D, Bezjak A, Clark G, Santabarbara P, Seymour L. Erlotinib in previously treated non-small-cell lung cancer. N. Engl. J. Med., 353, 123–132 (2005).

2. 2) Ellis PM, Coakley N, Feld R, Kuruvilla S, Ung YC. Use of the epidermal growth factor receptor inhibitors gefitinib, erlotinib, afatinib, dacomitinib, and icotinib in the treatment of non-small-cell lung cancer: a systematic review. Curr. Oncol., 22, e183–e215 (2015).

3. 3) Rosell R, Carcereny E, Gervais R, Vergnenegre A, Massuti B, Felip E, Palmero R, Garcia-Gomez R, Pallares C, Sanchez JM, Porta R, Cobo M, Garrido P, Longo F, Moran T, Insa A, De Marinis F, Corre R, Bover I, Illiano A, Dansin E, de Castro J, Milella M, Reguart N, Altavilla G, Jimenez U, Provencio M, Moreno MA, Terrasa J, Munoz-Langa J, Valdivia J, Isla D, Domine M, Molinier O, Mazieres J, Baize N, Garcia-Campelo R, Robinet G, Rodriguez-Abreu D, Lopez-Vivanco G, Gebbia V, Ferrera-Delgado L, Bombaron P, Bernabe R, Bearz A, Artal A, Cortesi E, Rolfo C, Sanchez-Ronco M, Drozdowskyj A, Queralt C, de Aguirre I, Ramirez JL, Sanchez JJ, Molina MA, Taron M, Paz-Ares L. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol., 13, 239–246 (2012).

4. 4) Binder D, Buckendahl AC, Hubner RH, Schlattmann P, Temmesfeld-Wollbruck B, Beinert T, Suttorp N. Erlotinib in patients with advanced non-small-cell lung cancer: impact of dose reductions and a novel surrogate marker. Med. Oncol., 29, 193–198 (2012).

5. 5) Reck M, Mok T, Wolf J, Heigener D, Wu YL. Reviewing the safety of erlotinib in non-small cell lung cancer. Expert Opin. Drug Saf., 10, 147–157 (2011).

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3