Tissue-Clearing Techniques Enable Three-Dimensional Visualization of Aerosolized Model Compound and Lung Structure at the Alveolar Scale

Author:

Togami Kohei1,Kitayama Anri1,Daisho Takayuki1,Wang Rui1,Tada Hitoshi1,Chono Sumio1

Affiliation:

1. Division of Pharmaceutics, Hokkaido Pharmaceutical University School of Pharmacy

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference23 articles.

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2. 2) Restrepo MI, Chalmers JD, Song Y, Mallow C, Hewlett J, Maldonado F, Yarmus L. Year in review 2016: respiratory infections, acute respiratory distress syndrome, pleural diseases, lung cancer and interventional pulmonology. Respirology, 22, 602–611 (2017).

3. 3) Suzuki A, Kondoh Y. The clinical impact of major comorbidities on idiopathic pulmonary fibrosis. Respir. Investig., 55, 94–103 (2017).

4. 4) Chao YC, Chang SF, Lu SC, Hwang TC, Hsieh WH, Liaw J. Ethanol enhanced in vivo gene delivery with non-ionic polymeric micelles inhalation. J. Control. Release, 118, 105–117 (2007).

5. 5) Garbuzenko OB, Mainelis G, Taratula O, Minko T. Inhalation treatment of lung cancer: the influence of composition, size and shape of nanocarriers on their lung accumulation and retention. Cancer Biol. Med., 11, 44–55 (2014).

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