Fluorescence Analysis of the Mitochondrial Effect of a Plasmalemmal Na+/Ca2+ Exchanger Inhibitor, SEA0400, in Permeabilized H9c2 Cardiomyocytes

Author:

Namekata Iyuki1,Hamaguchi Shogo1,Iida-Tanaka Naoko12,Kusakabe Taichi3,Kato Keisuke3,Kawanishi Toru4,Tanaka Hikaru1

Affiliation:

1. Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University

2. Department of Food Science, Otsuma Women’s University

3. Department of Organic Chemistry, Faculty of Pharmaceutical Sciences, Toho University

4. National Institute of Health Sciences

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference20 articles.

1. 1) Bers DM, Despa S. Cardiac myocytes Ca2+ and Na+ regulation in normal and failing hearts. J. Pharmacol. Sci., 100, 315–322 (2006).

2. 2) Matsuda T, Arakawa N, Takuma K, Kishida Y, Kawasaki Y, Sakaue M, Takahashi K, Takahashi T, Suzuki T, Ota T, Hamano-Takahashi A, Onishi M, Tanaka Y, Kameo K, Baba A. SEA0400, a novel and selective inhibitor of the Na+–Ca2+ exchanger, attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models. J. Pharmacol. Exp. Ther., 298, 249–256 (2001).

3. 3) Tanaka H, Nishimaru K, Aikawa T, Hirayama W, Tanaka Y, Shigenobu K. Effect of SEA0400, a novel inhibitor of sodium–calcium exchanger, on myocardial ionic currents. Br. J. Pharmacol., 135, 1096–1100 (2002).

4. 4) Matsuda T, Koyama Y, Baba A. Functional proteins involved in regulation of intracellular Ca2+ for drug development: pharmacology of SEA0400, a specific inhibitor of the Na+–Ca2+ exchanger. J. Pharmacol. Sci., 97, 339–343 (2005).

5. 5) Tanaka H, Namekata I, Takeda K, Kazama A, Shimizu Y, Moriwaki R, Hirayama W, Sato A, Kawanishi T, Shigenobu K. Unique excitation-contraction characteristics of mouse myocardium as revealed by SEA0400, a specific inhibitor of Na+–Ca2+ exchanger. Naunyn Schmiedebergs Arch. Pharmacol., 371, 526–534 (2005).

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3