Associations between Lifestyle-Related Diseases and Transporters Involved in Intestinal Absorption and Biliary Excretion of Cholesterol
Author:
Affiliation:
1. Department of Pharmacy, the University of Tokyo Hospital, Faculty of Medicine, the University of Tokyo
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/41/1/41_b17-00690/_pdf
Reference90 articles.
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2. 2) Temel RE, Tang W, Ma Y, Rudel LL, Willingham MC, Ioannou YA, Davies JP, Nilsson LM, Yu L. Hepatic Niemann–Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe. J. Clin. Invest., 117, 1968–1978 (2007).
3. 3) Yu L, Hammer RE, Li-Hawkins J, Von Bergmann K, Lutjohann D, Cohen JC, Hobbs HH. Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion. Proc. Natl. Acad. Sci. U.S.A., 99, 16237–16242 (2002).
4. 4) Yu L, Li-Hawkins J, Hammer RE, Berge KE, Horton JD, Cohen JC, Hobbs HH. Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J. Clin. Invest., 110, 671–680 (2002).
5. 5) Davies JP, Levy B, Ioannou YA. Evidence for a Niemann–Pick C (NPC) gene family: identification and characterization of NPC1L1. Genomics, 65, 137–145 (2000).
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